Solanum trilobatum is widely used to treat respiratory ailments such as cough, cold, bronchitis, and asthma. It is believed to have expectorant properties that help loosen phlegm and clear airways. The plant is known for its anti-inflammatory effects, which can help reduce swelling and pain associated with conditions like arthritis and joint inflammation.

Solanum trilobatum contains antioxidants such as flavonoids and phenolic compounds, which help neutralize harmful free radicals in the body. This antioxidant activity contributes to overall health and may protect cells from oxidative stress. It is used to improve digestion and stimulate appetite. Solanum trilobatum is often consumed in the form of decoctions or infusions to support gastrointestinal health. It is used traditionally to treat urinary disorders and promote kidney health.Solanum trilobatum may have potential anti-diabetic effects, helping to regulate blood sugar levels.